The Tribes consist of the mutated successors of earlier humans that were affected by the Plague but survived and emerged stronger, wielding strange new powers and abilities. The Tribes are organized in loose alliances and have no central leadership. Instead, every Tribe is led by its own High Priest.

The Tribes are not entirely foreign to technology but the mutants prefer to rely on their paranormal abilities, or ‘magic’. Since xenolite is key for unlocking the higher levels of the mutants’ psychic energy, the Tribes always build their settlements around rich xenolite deposits, tend to the xenolite, and move on when it expires.